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1

Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products

Siveen, Kodappully S., Prabhu, Kirti S., Achkar, Iman W., Kuttikrishnan, Shilpa, Shyam, Sunitha, Khan, Abdul Q., Merhi, Maysaloun, Dermime, Said, Uddin, Shahab

Journal:

Molecular Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2018

2

Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications

Sher, Gulab, Salman, Nadia Aziz, Khan, Abdul Q., Prabhu, Kirti S., Raza, Afsheen, Kulinski, Michal, Dermime, Said, Haris, Mohammad, Junejo, Kulsoom, Uddin, Shahab

Journal:

Seminars in Cancer Biology

Année:

2020

Fichier:

PDF, 3.10 MB

2020

3

Use of adenoviruses encoding CD40L or IL-2 against B cell lymphoma

El Kahina Meziane, Tapan Bhattacharyya, Anne C. Armstrong, Cheng Qian, Robert E. Hawkins, Peter L. Stern, Said Dermime

Journal:

International Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 218 KB

english, 2004

4

Cd8 T-cell recognition of human 5T4 oncofetal antigen

Lucy JC Smyth, Eyad Elkord, Taher E.I. Taher, Hui-Rong Jiang, Deborah J. Burt, Alison Clayton, Peter A. van Veelen, Arnoud de Ru, Ferry Ossendorp, Cornelis J. M. Melief, Jan W. Drijfhout, Said Dermime

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 316 KB

english, 2006

5

Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells

Hazem Ghebeh, Asma Tulbah, Shamayel Mohammed, Naser ElKum, Suad M. Bin Amer, Taher Al-Tweigeri, Said Dermime

Journal:

International Journal of Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 825 KB

english, 2007

6

Alloreactive CD4+ T lymphocytes can exert cytotoxicity to chronic myeloid leukaemia cells processing and presenting exogenous antigen

Yin-zheng Jiang, Dimitrios Mavroudis, Said Dermime, Nancy Hensel, Daniel Couriel, Jeffrey Molldrem, A. John Barrett

Journal:

British Journal of Haematology

Année:

1996

Langue:

english

Fichier:

PDF, 407 KB

english, 1996

7

Specific depletion of alloreactive T cells in HLA-identical siblings: a method for separating graft-versus-host and graft-versus-leukaemia reactions

Mavroudis, Dermime, Molldrem, Jiang, Raptis, Van Rhee, Hensel, Fellowes, Eliopoulos, Barrett

Journal:

British Journal of Haematology

Année:

1998

Langue:

english

Fichier:

PDF, 428 KB

english, 1998

8

Interaction of natural killer cells with MHC class II: reversal of HLA-DR1-mediated protection of K562 transfectant from natural killer cell-mediated cytolysis by brefeldin-A

Y. Z. JIANG, D. COURIEL, D. A. MAVROUDIS, P. LEWALLE, V. MALKOVSKA, N. F. HENSEL, S. DERMIME, J. MOLLDREM, A. J. BARRETT

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 746 KB

english, 1996

9

Preferential usage of T cell receptor (TCR) V β by allogeneic T cells recognizing myeloid leukemia cells: implications for separating graft-versus-leukemia effect from graft-versus-host disease

Jiang, Y-Z, Mavroudis, D A, Dermime, S, Molldrem, J, Hensel, N F, Barrett, A J

Journal:

Bone Marrow Transplantation

Année:

1997

Langue:

english

Fichier:

PDF, 85 KB

english, 1997

10

Immune escape from a graft-versus-leukemia effect may play a role in the relapse of myeloid leukemias following allogeneic bone marrow transplantation

Dermime, S, Mavroudis, D, Jiang, Y-Z, Hensel, N, Molldrem, J, Barrett, A J

Journal:

Bone Marrow Transplantation

Année:

1997

Langue:

english

Fichier:

PDF, 283 KB

english, 1997

11

Developing effective cancer vaccines: design and monitoring are critical

Armstrong, A, Dermime, S

Journal:

British Journal of Cancer

Année:

2001

Langue:

english

Fichier:

PDF, 45 KB

english, 2001

12

Vaccine and antibody-directed T cell tumour immunotherapy

Said Dermime, David E Gilham, David M Shaw, Emma J Davidson, El-Kahina Meziane, Anne Armstrong, Robert E Hawkins, Peter L Stern

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 929 KB

english, 2004

13

FOXP3+Tregsand B7-H1+/PD-1+T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy

Hazem Ghebeh, Eman Barhoush, Asma Tulbah, Naser Elkum, Taher Al-Tweigeri, Said Dermime

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2008

14

CD8+ cytotoxic T lymphocytes generated against a WT1 peptide analog enhance the lytic activity of leukemic cells

G. Al Qudaihi, C. Lehe, M. Negash, M. Al-Alwan, H. Ghebeh, S.Y. Mohamed, A.J.M. Saleh, A. Dickinson, M. Aljurf, S. Dermime

Journal:

European Journal of Cancer Supplements

Année:

2008

Langue:

english

Fichier:

PDF, 85 KB

english, 2008

15

The WT1 antigen as a novel target for human leukemia-specific CD4+ T regulatory T cells

S. Dermime, C. Lehe, H. Ghebeh, A. Al-Sulaiman, G. Al Qudaihi, K. Al-Hussein, F. Almohareb, N. Chaudhri, H. Al-Zahrani, M. Aljurf

Journal:

European Journal of Cancer Supplements

Année:

2008

Langue:

english

Fichier:

PDF, 85 KB

english, 2008

16

Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: The Saudi Arabia experience

Naser Elkum, Said Dermime, Dahish Ajarim, Ali Al-Zahrani, Adher Alsayed, Asma Tulbah, Osama Al Malik, Mohamed Alshabanah, Adnan Ezzat, Taher Al-Tweigeri

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 278 KB

english, 2007

17

Elevated expression of the toll like receptors 2 and 4 in obese individuals: its significance for obesity-induced inflammation

Rasheed Ahmad, Anfal Al-Mass, Valerie Atizado, Asma Al-Hubail, Fahad Al-Ghimlas, Monira Al-Arouj, Abdullah Bennakhi, Said Dermime, Kazem Behbehani

Journal:

Journal of Inflammation

Année:

2012

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2012

18

The immunoinhibitory B7-H1 molecule as a potential target in cancer: Killing many birds with one stone

Afreen, Sehar, Dermime, Said

Journal:

Hematology/Oncology and Stem Cell Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2014

19

WT1 peptide analogue WT1-126Y enhances leukemia lysis

Alqudaihi, Ghofran, Lehe, Cynthia, Al-Alwan, Monther, Ghebeh, Hazem, Dickinson, Anne, Dermime, Said

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 76 KB

english, 2014

20

Overexpression of the cancer-related DUSP1 gene in human obesity and its modulation by physical exercise

Khadir, Abdelkrim, Tiss, Ali, Abubaker, Jehad, Abu-farha, Mohamed, Dermime, Said, Dehbi, Mohammed

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 72 KB

english, 2014

21

IL-33 is negatively associated with the BMI and confers a protective lipid/metabolic profile in non-diabetic but not diabetic subjects

Hasan, Amal, Al-Ghimlas, Fahad, Warsame, Samia, Al-Hubail, Asma, Ahmad, Rasheed, Bennakhi, Abdullah, Al-Arouj, Monira, Behbehani, Kazem, Dehbi, Mohammed, Dermime, Said

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 905 KB

english, 2014

22

MAP kinase phosphatase DUSP1 is overexpressed in obese humans and modulated by physical exercise

Khadir, A., Tiss, A., Abubaker, J., Abu-Farha, M., Al-Khairi, I., Cherian, P., John, J., Kavalakatt, S., Warsame, S., Al-Madhoun, A., Al-Ghimlas, F., Elkum, N., Behbehani, K., Dermime, S., Dehbi, M.

Journal:

AJP Endocrinology and Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 637 KB

english, 2015

23

The Role of the Immune System in Anti-Tumour Responses

Said Dermime,John Barrett,Dr Carlo Gambacorti-Passerini

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 2.07 MB

english, 1995

24

Therapeutic targeting of B7-H1 in breast cancer

Hasan, Amal, Ghebeh, Hazem, Lehe, Cynthia, Ahmad, Rasheed, Dermime, Said

Journal:

Expert Opinion on Therapeutic Targets

Année:

2011

Langue:

english

Fichier:

PDF, 886 KB

english, 2011

25

Acute Promyelocytic Leukaemia Cells Resistant to Retinoic Acid Show Further Perturbation of the RARα Signal Transduction System

Dermime, Said, Grignani, Francesco, Rogaia, Daniela, Liberatore, Concetta, Marchesi, Edoardo, Gambacorti-Passerini, Carlo

Journal:

Leukemia and Lymphoma

Année:

1995

Langue:

english

Fichier:

PDF, 614 KB

english, 1995

26

The Wilms' Tumor Antigen Is a Novel Target for Human CD4+ Regulatory T Cells: Implications for Immunotherapy

Lehe, C., Ghebeh, H., Al-Sulaiman, A., Al Qudaihi, G., Al-Hussein, K., Almohareb, F., Chaudhri, N., Alsharif, F., Al-Zahrani, H., Tbakhi, A., Aljurf, M., Dermime, S.

Journal:

Cancer Research

Année:

2008

Langue:

english

Fichier:

PDF, 650 KB

english, 2008

27

Comment on "Characterization of Human Lung Tumor-Associated Fibroblasts and Their Ability to Modulate the Activation of Tumor-Associated T Cells"

Ghebeh, H., Dermime, S.

Journal:

The Journal of Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 337 KB

english, 2007

28

Breast Carcinoma-Associated Fibroblasts and Their Counterparts Display Neoplastic-Specific Changes

Hawsawi, N. M., Ghebeh, H., Hendrayani, S.-F., Tulbah, A., Al-Eid, M., Al-Tweigeri, T., Ajarim, D., Alaiya, A., Dermime, S., Aboussekhra, A.

Journal:

Cancer Research

Année:

2008

Langue:

english

Fichier:

PDF, 980 KB

english, 2008

29

Cancer vaccines and immunotherapy

Journal:

British Medical Bulletin

Année:

2002

Langue:

english

Fichier:

PDF, 111 KB

english, 2002

30

Immunization with a Recombinant Adenovirus Encoding a Lymphoma Idiotype: Induction of Tumor-Protective Immunity and Identification of an Idiotype-Specific T Cell Epitope

Armstrong, A. C., Dermime, S., Allinson, C. G., Bhattacharyya, T., Mulryan, K., Gonzalez, K. R., Stern, P. L., Hawkins, R. E.

Journal:

The Journal of Immunology

Année:

2002

Langue:

english

Fichier:

PDF, 202 KB

english, 2002

31

Current advances, problems and prospects for vaccine-based immunotherapy in follicular non-Hodgkin's lymphoma

Dermime, Said, Aljurf, Mahmoud D

Journal:

Leukemia and Lymphoma

Année:

2005

Langue:

english

Fichier:

PDF, 310 KB

english, 2005

32

Paraneoplastic neuromyelitis optica spectrum disorder associated with stomach carcinoid tumor

Al-Harbi, Talal, Al-Sarawi, Adnan, Binfalah, Mohamed, Dermime, Said

Journal:

Hematology/Oncology and Stem Cell Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 636 KB

english, 2014

33

Adoptive Transfer of Anti-idiotypic T Cells Cure Mice of Disseminated B Cell Lymphoma

Armstrong, Anne C., Dermime, Said, Mulryan, Kate, Stern, Peter L., Bhattacharyya, Tapan, Hawkins, Robert E.

Journal:

Journal of Immunotherapy

Année:

2004

Langue:

english

Fichier:

PDF, 130 KB

english, 2004

34

Cancer Stem Cell Immunotherapy: the Right Bullet for the Right Target

Ghebeh, Hazem, Dermime, Said, Bakr, Mohammad Mahmoud

Journal:

Hematology/Oncology and Stem Cell Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 570 KB

english, 2008

35

Identification of a novel peptide derived from the M-phase phosphoprotein 11 (MPP11) leukemic antigen recognized by human CD8+ cytotoxic T lymphocytes

Al Qudaihi, Ghofran, Lehe, Cynthia, Dickinson, Anne, Eltayeb, Khaled, Rasheed, Walid, Chaudhri, Naeem, Aljurf, Mahmoud, Dermime, Said

Journal:

Hematology/Oncology and Stem Cell Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2010

36

GENETIC APPROACHES TO VACCINATION FOR LYMPHOMA

Allinson, C.G., Whittington, H.A., Ashworth, L.J., Bhattacharyya, T.P., Dermime, S., Hawkins, R.E.

Journal:

Biochemical Society Transactions

Année:

1999

Langue:

english

Fichier:

PDF, 156 KB

english, 1999

37

Lack of T-cell-mediated recognition of the fusion region of the pml/RAR-$\alpha$ hybrid protein by lymphocytes of acute promyelocytic leukemia patients

Dermime, Said, Bertazzoli, Carla, Marchesi, Edoardo, Ravagnani, Fernando, Blaser, Kurt, Corneo, Gian Marco, Pogliani, Enrico, Parmiani, Giorgio, Gambacorti-Passerini, Carlo

Journal:

Clinical Cancer Research

Année:

1996

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1996

38

Hematopoietic stem cell transplantation in qatar: One-year anniversary

Bakr, Mohammad, Al-Hijji, Ibrahim, Menasria, Naziha, Merenkov, Zeyd, Al-Azzawi, Safaa, Taha, Ruba, Gulied, Amaal, Gillespie, Catherine Anne, Dermime, Said, Liakopoulou, Effie, Knuth, Alexander

Journal:

Hematology/Oncology and Stem Cell Therapy

Année:

2017

Langue:

english

Fichier:

PDF, 497 KB

english, 2017

39

Dysregulated expression of SKP2 and its role in hematological malignancies

Kulinski, Michal, Achkar, Iman W., Haris, Mohammad, Dermime, Said, Mohammad, Ramzi R., Uddin, Shahab

Journal:

Leukemia and Lymphoma

Année:

2017

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2017

40

RAS-mediated oncogenic signaling pathways in human malignancies

Khan, Abdul Q., Kuttikrishnan, Shilpa, Siveen, Kodappully S., Prabhu, Kirti S., Shanmugakonar, Muralitharan, Al Naemi, Hamda, Haris, Mohammad, Dermime, Said, Uddin, Shahab

Journal:

Seminars in Cancer Biology

Année:

2018

Langue:

english

Fichier:

PDF, 614 KB

english, 2018

41

Interaction of Osteopontin with IL-18 in Obese Individuals: Implications for Insulin Resistance

Ahmad, Rasheed, Al-Mass, Anfal, Al-Ghawas, Dalal, Shareif, Nada, Zghoul, Nadia, Melhem, Motasem, Hasan, Amal, Al-Ghimlas, Fahad, Dermime, Said, Behbehani, Kazem, López-Lluch, Guillermo

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 888 KB

english, 2013

42

NY-ESO-1 Based Immunotherapy of Cancer: Current Perspectives

Thomas, Remy, Al-Khadairi, Ghaneya, Roelands, Jessica, Hendrickx, Wouter, Dermime, Said, Bedognetti, Davide, Decock, Julie

Journal:

Frontiers in Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 501 KB

english, 2018

43

Role of Epstein–Barr Virus in the Pathogenesis of Head and Neck Cancers and Its Potential as an Immunotherapeutic Target

Fernandes, Queenie, Merhi, Maysaloun, Raza, Afsheen, Inchakalody, Varghese Philipose, Abdelouahab, Nassima, Zar Gul, Abdul Rehman, Uddin, Shahab, Dermime, Said

Journal:

Frontiers in Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 2.93 MB

english, 2018

44

Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines

Prabhu, Kirti S., Siveen, Kodappully Sivaraman, Kuttikrishnan, Shilpa, Iskandarani, Ahmad N., Khan, Abdul Q., Merhi, Maysaloun, Omri, Halima E., Dermime, Said, El-Elimat, Tamam, Oberlies, Nicholas H.,

Journal:

Frontiers in Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2018

45

Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia

Kuttikrishnan, Shilpa, Siveen, Kodappully S., Prabhu, Kirti S., Khan, Abdul Quaiyoom, Akhtar, Sabah, Mateo, Jericha M., Merhi, Maysaloun, Taha, Ruba, Omri, Halima El, Mraiche, Fatima, Dermime, Said, U

Journal:

Leukemia and Lymphoma

Année:

2018

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2018

46

Curcumin-Mediated Degradation of S-Phase Kinase Protein 2 Induces Cytotoxic Effects in Human Papillomavirus-Positive and Negative Squamous Carcinoma Cells

Khan, Abdul Q., Siveen, Kodappully S., Prabhu, Kirti S., Kuttikrishnan, Shilpa, Akhtar, Sabah, Shaar, Abdullah, Raza, Afsheen, Mraiche, Fatima, Dermime, Said, Uddin, Shahab

Journal:

Frontiers in Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2018

47

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation

Siveen, Kodappully S., Prabhu, Kirti S., Parray, Aeijaz S., Merhi, Maysaloun, Arredouani, Abdelilah, Chikri, Mohamed, Uddin, Shahab, Dermime, Said, Mohammad, Ramzi M., Steinhoff, Martin, Janahi, Ibrah

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 5.23 MB

2019

48

Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines

Prabhu, Kirti, Siveen, Kodappully, Kuttikrishnan, Shilpa, Jochebeth, Anh, Ali, Tayyiba, Elareer, Noor, Iskandarani, Ahmad, Quaiyoom Khan, Abdul, Merhi, Maysaloun, Dermime, Said, El-Elimat, Tamam, Ober

Journal:

Année:

2019

Fichier:

PDF, 2.45 MB

2019

49

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer

Siveen, Kodappully S., Raza, Afsheen, Ahmed, Eiman I., Khan, Abdul Q., Prabhu, Kirti S., Kuttikrishnan, Shilpa, Mateo, Jericha M., Zayed, Hatem, Rasul, Kakil, Azizi, Fouad, Dermime, Said, Steinhoff, M

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2019

50

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia

Kuttikrishnan, Shilpa, Siveen, Kodappully S., Prabhu, Kirti S., Khan, Abdul Quaiyoom, Ahmed, Eiman I., Akhtar, Sabah, Ali, Tayyiba A., Merhi, Maysaloun, Dermime, Said, Steinhoff, Martin, Uddin, Shahab

Journal:

Frontiers in Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 7.17 MB

english, 2019